BioBlocks’ CFL: Designed for Improved Lead Discovery

BioBlocks’ CFL: Designed for Improved Lead Discovery

Screenable compounds in BioBlocks’ newly available Comprehensive Fragment Library (CFL) are selected for their improved chemical and pharmaceutical properties. Unlike traditional fragment screening sets of predominantly flat aromatic compounds, the typical CFL fragment features both aromatic and sp3 character in 15 atoms or less, with >95% containing handles for further synthetic elaboration. Many of our CFL fragments also have uncommon or rare core structures, enabling access to unique regions of medicinal chemistry space.

CFL is a major component of BioBlocks’ new Leap-to-Lead™ drug discovery platform. Contact us for more information on obtaining CFL plates for screening.




About the Author and BIOCOM CRO Board Member