Aquinox Pharmaceuticals, Inc.

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We are a clinical-stage pharmaceutical company discovering and developing targeted therapeutics in disease areas of inflammation and immuno-oncology. Our primary focus is anti-inflammatory product candidates targeting SH2-containing inositol-5′-phosphatase 1, or SHIP1, which is a key regulator of an important cellular signaling pathway in immune cells, known as the PI3K pathway. Our lead product candidate, AQX-1125, is a small molecule activator of SHIP1 suitable for oral, once daily dosing. Having successfully completed multiple preclinical studies and seven clinical trials with AQX-1125, we are now advancing towards pivotal Phase 3 trials with AQX-1125 in our lead indication of bladder pain syndrome/interstitial cystitis (BPS/IC). Aquinox has a broad intellectual property portfolio and pipeline of preclinical drug candidates that activate SHIP1.

Contact

Paul Brennan Vice President, Business Development Phone: 604-901-3037
Brendan Payne Associate Director, Investor Relations Phone: 604-901-3019
www.aqxpharma.com
1150 Bayhill Drive, Suite 200 CA San Bruno, CA 94066